Research Article Omics of probiotic bacteria: which features to seek?

L. Castro-Oliveira (1, 2) , M.O. O Silva (2) , R.D.O. D O Carvalho (1, 3) , A. Anchiêta (2) , L.J. J Benevides (1, 2) , Gwénaël Jan (4) , C.J.F. J F Oliveira (2) , H.C.P. C P Figueiredo (5) , V.A.C. a C Azevedo (1) , S.C. C Soares (1, 2)

1 Laboratory of Cellular and Molecular Genetics
2 Universidade Federal do Triângulo Mineiro Uberaba
3 Sechenov First Moscow State Medical University [Russia]
4 STLO - Science et Technologie du Lait et de l'Oeuf
5 ICB - Instituto de Ciencias Biologicas [Minas Gerais]

Probiotics are live nonpathogenic microorganisms extensively used in food, pharmaceutical and medicinal industries. Recently, attention has focused on specific features of probiotics and on the abilities of some long known and recently described species of this group. In general, desired features of probiotics include resistance to acid and bile salts to avoid dysbiosis and induction of immune system development. The advent of next-generation sequencing technology has propelled the genomic area, allowing a search for probiotic features in a wide range of probiotic species, especially bacteria. In this context, functional genomics analyses can help interpret big data, correlating the findings with comparative genomics analyses, in a search for direct applications. To select the articles in this review, we used the following indexing terms: (probiotics OR probiosis) AND (genomics OR transcriptomics OR

Mots clés: Probiotic; dysbiosis; immune system; genomics analyses; transcriptomic; culturomic; metagenomic

Domaines: Alimentation et Nutrition

L. Castro-Oliveira, M.O. O Silva, R.D.O. D O Carvalho, A. Anchiêta, L.J. J Benevides, et al.. Research Article Omics of probiotic bacteria: which features to seek?. Genetics and molecular research : GMR, 2020, 19 (2), ⟨10.4238/gmr18599⟩. ⟨hal-02983918⟩